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Please use this identifier to cite or link to this item: http://hdl.handle.net/10119/4506

Title: Fluorescence modulation of long DNA molecules adsorbed onto a microelectrode surface
Authors: Ueda, Masanori
Takai, Madoka
Taniguchi, Kazutake
Takamura, Yuzuru
Horiike, Yasuhiro
Baba, Yoshinobu
Issue Date: 2003-12-15
Publisher: American Institute of Physics
Magazine name: Applied Physics Letters
Volume: 83
Number: 24
Start page: 5086
End page: 5088
DOI: 10.1063/1.1633333
Abstract: Using microfabricated electrodes, we demonstrate fluorescence modulation of deoxyribonucleic acid (DNA) stained with dye through the application of cyclic electric fields. The fluorescence of DNA adsorbed onto an electrode was quenched under the potentials greater than about 1 V, and was recovered by reducing the potentials to below about 0.6 V. The quenching was observed even for a single DNA molecule adsorbed on an electrode. Therefore, the fluorescence modulation of DNA by external electric fields can be expected as one of selective detection methods for adsorbed DNA onto electrodes.
Rights: Copyright 2003 American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics. The following article appeared in M. Ueda, M. Takai, K. Taniguchi, Y. Takamura, Y. Horiike, Y. Baba, Applied Physics Letters, 83(24), 5086-5088 (2003) and may be found at http://link.aip.org/link/?APPLAB/83/5086/1
URI: http://hdl.handle.net/10119/4506
Material Type: publisher
Appears in Collections:c10-1. 雑誌掲載論文 (Journal Articles)

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