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Please use this identifier to cite or link to this item: http://hdl.handle.net/10119/4514

Title: Electrophoresis of long deoxyribonucleic acid in curved channels: The effect of channel width on migration dynamics
Authors: Ueda, Masanori
Hayama, Tetsuya
Takamura, Yuzuru
Horiike, Yasuhiro
Dotera, Tomonari
Baba, Yoshinobu
Issue Date: 2004-09-01
Publisher: American Institute of Physics
Magazine name: Journal of Applied Physics
Volume: 96
Number: 5
Start page: 2937
End page: 2944
DOI: 10.1063/1.1776625
Abstract: We investigated the dynamics of long deoxyribonucleic acid (DNA) migrating through curved channels under electric fields. Long DNA exhibits large conformational changes in the curved channels because of the inhomogeneity of the electric fields around curves. Two kinds of channel shapes were used for the examination. One (type I) has the same width in the curved region as in the straight region. The other (type II) is wider in the curved region than in the straight region. The difference in migration rates between long DNA and short DNA was larger in type II than in type I chips. We discuss the separation mechanism of the type II chip.
Rights: Copyright 2004 American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics. The following article appeared in M. Ueda, T. Hayama, Y. Takamura, Y. Horiike, T. Dotera, Y. Baba, Journal of Applied Physics, 96(5), 2937-2944 (2004) and may be found at http://link.aip.org/link/?JAPIAU/96/2937/1
URI: http://hdl.handle.net/10119/4514
Material Type: publisher
Appears in Collections:c10-1. 雑誌掲載論文 (Journal Articles)

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