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Please use this identifier to cite or link to this item: http://hdl.handle.net/10119/4874

Title: Evaluation of Lipoxygenase Inhibitory Activity of Anacardic Acids
Authors: Kubo, Isao
Joung Ha, Tae
Tsujimoto, Kazuo
Tocoli, Felismino E.
Green, Ivan R.
Keywords: Lipoxygenase
Anacardic Acids
Inhibitory Activity
Hydrophobicity
Issue Date: 2008
Publisher: Verlag der Zeitschrift für Naturforschung
Magazine name: Zeitschrift für Naturforschung C
Volume: 63c
Number: 7 / 8
Start page: 539
End page: 546
Abstract: 6-Alkylsalicylic acids inhibit the linoleic acid peroxidation catalyzed by soybean lipoxygenase-1 (EC 1.13.11.12, type 1) competitively and without pro-oxidant effects. This activity is largely dependent on the nature of their alkyl side chains. Inhibitory activities of anacardic acids, viz. 6-pentadec(en)ylsalicylic acids, isolated from the cashew Anacardium occidentale, were initially used for comparison because their aromatic head portions are the same. Consequently, the data should be interpreted to mean that changes in the hydrophobic side chain tail portions of the molecules evaluated correlate with the specific activity determined.
Rights: Copyright (c) 2008 Verlag der Zeitschrift für Naturforschung, Isao Kubo, Tae Joung Ha, Kazuo Tsujimoto, Felismino E. Tocoli, and Ivan R. Green, Zeitschrift für Naturforschung C, 63c(7 / 8), 2008, 539-546. This material is posted here with permission of the Verlag der Zeitschrift für Naturforschung.
URI: http://hdl.handle.net/10119/4874
Material Type: publisher
Appears in Collections:c10-1. 雑誌掲載論文 (Journal Articles)

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