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c10-1. 雑誌掲載論文 >
このアイテムの引用には次の識別子を使用してください:
http://hdl.handle.net/10119/9524
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| タイトル: | Manganese oxide nanoparticle-assisted laser desorption/ionization mass spectrometry for medical applications |
| 著者: | Taira, Shu
Kitajima, Kenji
Katayanagi, Hikaru
Ichiishi, Eiichiro
Ichiyanagi, Yuko |
| キーワード: | nano
metal oxide
transmission electron microscopy
ionization
mass spectrometry |
| 発行日: | 2009-07-14 |
| 出版者: | Institute of Physics and IOP Publishing Limited |
| 誌名: | Science and Technology of Advanced Materials |
| 巻: | 10 |
| 号: | 3 |
| 開始ページ: | 034602-1 |
| 終了ページ: | 034602-6 |
| DOI: | 10.1088/1468-6996/10/3/034602 |
| 抄録: | We prepared and characterized manganese oxide magnetic nanoparticles (d = 5.6 nm) and developed nanoparticle-assited laser desorption/ionization (nano-PALDI) mass spectrometry. The nanoparticles had MnO2 and Mn2O3 core conjugated with hydroxyl and amino groups、 and showed paramagnetism at room temperature. The nanoparticles worked as an ionization assistng reagent in mass spectroscopy. The mass spectra showed no background in the low m/z. The nanoparticles could ionize the samples of peptide、 drug and proteins (approx. 5、000 Da) without using matrix、 i.e. 2、5-dihydroxybenzoic acid (DHB)、 4-hydroxy-α-cinnamic acid (CHCA) and liquid matrix、 as conventional ionization assisting reagents. Post source decay spectra by nano-PALDI mass spectrometry will yield information of chemical structure of analyte. |
| Rights: | Copyright (C) Institute of Physics and IOP Publishing Limited 2009. This is the author-created version of Institute of Physics and IOP Publishing Limited, Shu Taira, Kenji Kitajima, Hikaru Katayanagi, Eiichiro Ichiishi and Yuko Ichiyanagi, Science and Technology of Advanced Materials, 10(3), 2009, 034602-1-034602-6. http://dx.doi.org/10.1088/1468-6996/10/3/034602 |
| URI: | http://hdl.handle.net/10119/9524 |
| 資料タイプ: | publisher |
| 出現コレクション: | c10-1. 雑誌掲載論文 (Journal Articles)
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このアイテムのファイル:
| ファイル |
記述 |
サイズ | 形式 |
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| 13713-1.pdf | | 809Kb | Adobe PDF | 見る/開く |
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