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Please use this identifier to cite or link to this item: http://hdl.handle.net/10119/9555

Title: Photochemical control on morphologies of a cell-sized synthetic vesicle
Authors: Hamada, Tsutomu
Ishii, Ken-ichi
Sugimoto, Ryoko
Nagasaki, Takeshi
Takagi, Masahiro
Keywords: cell-sized liposomes
giant vesicles
photo-isomerization
morphological transition
model membranes
Issue Date: 2009-11
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Magazine name: International Symposium on Micro-NanoMechatronics and Human Science, 2009. MHS 2009
Start page: 161
End page: 165
DOI: 10.1109/MHS.2009.5352045
Abstract: By using a synthetic photosensitive amphiphile containing azobenzene (KAON12), we developed a method for the photo-manipulation of lipid membrane morphology, in which the shape of a vesicle can be switched by light. Cell-sized liposomes are prepared from KAON12 and 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC). We conducted real-time observations of vesicular transformation in the photo-sensitive liposome by phase-contrast microscopy, and found that membrane budding transitions could be controlled by light. These transformations can be interpreted in terms of the change in the effective membrane surface area due to photoisomerization of the constituent molecules. We discuss the mechanism by considering the elastic free energy of the membranes.
Rights: Copyright (C) 2009 IEEE. Reprinted from International Symposium on Micro-NanoMechatronics and Human Science, 2009. MHS 2009, 161-165. This material is posted here with permission of the IEEE. Such permission of the IEEE does not in any way imply IEEE endorsement of any of JAIST's products or services. Internal or personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution must be obtained from the IEEE by writing to pubs-permissions@ieee.org. By choosing to view this document, you agree to all provisions of the copyright laws protecting it.
URI: http://hdl.handle.net/10119/9555
Material Type: publisher
Appears in Collections:c11-1. 会議発表論文 (Conference Papers)

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