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c11-1. 会議発表論文 >
このアイテムの引用には次の識別子を使用してください:
http://hdl.handle.net/10119/9556
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| タイトル: | Assembly of Ag@Au Nanoparticles Using Complementary Stranded DNA Molecules and Their Detection Using UV-Vis and Raman Spectroscopic Techniques |
| 著者: | Mott, Derrick
Nguyen, T. B. Thuy
Aoki, Yoshiya
Maenosono, Shinya |
| キーワード: | Assembly
DNA
Sensing
Ag@Au |
| 発行日: | 2010 |
| 出版者: | Materials Research Society |
| 誌名: | Materials Research Society Symposium Proceedings |
| 巻: | 1272 |
| 開始ページ: | PP06-12 |
| DOI: | 10.1557/PROC-1272-PP06-12 |
| 抄録: | Silver nanoparticles coated by a layer of gold (Ag@Au) have received much attentionbecause of their potential application as ultra sensitive probes for the detection of biologicallyimportant molecules such as DNA, proteins, amino acids and many others. However, the abilityto control the size, shape, and monodispersity of the Ag@Au structure has met with limitedsuccess. In our own research we have addressed this challenge by creating an aqueous wetchemical synthesis technique towards size and shape controllable Ag@Au nanoparticles. Thesematerials are highly interesting because of the tunable silver core size, and the tunable gold shellthickness, opening many avenues to the modification of the particle properties in terms of biomolecularsensing. The resulting nanoparticle probes were functionalized with twocomplementary stranded DNA oligonucleotides. When combined, the complementary strandshybridized, causing the Ag@Au nanoparticles to assemble into large nano-structures. Thepresence of the oligonucleotide was confirmed through a series of techniques including UV-Visand Raman spectroscopy, as well as TEM, XPS, DLS, and many others. The results reflect therole that the nanoparticle physical properties play in the detection of the bio-molecules, as wellas elucidate the characteristics of the bio-molecule/nanoparticle interaction. |
| Rights: | Copyright (C) 2010 Materials Research Society. It is posted here by permission of the Materials Research Society. Derrick Mott, Nguyen T. B. Thuy, Yoshiya Aoki, and Shinya Maenosono, Materials Research Society Symposium Proceedings, 1272, 2010, PP06-12. http://www.mrs.org/ |
| URI: | http://hdl.handle.net/10119/9556 |
| 資料タイプ: | publisher |
| 出現コレクション: | c11-1. 会議発表論文 (Conference Papers)
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