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Please use this identifier to cite or link to this item:
http://hdl.handle.net/10119/9556
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| Title: | Assembly of Ag@Au Nanoparticles Using Complementary Stranded DNA Molecules and Their Detection Using UV-Vis and Raman Spectroscopic Techniques |
| Authors: | Mott, Derrick
Nguyen, T. B. Thuy
Aoki, Yoshiya
Maenosono, Shinya |
| Keywords: | Assembly
DNA
Sensing
Ag@Au |
| Issue Date: | 2010 |
| Publisher: | Materials Research Society |
| Magazine name: | Materials Research Society Symposium Proceedings |
| Volume: | 1272 |
| Start page: | PP06-12 |
| DOI: | 10.1557/PROC-1272-PP06-12 |
| Abstract: | Silver nanoparticles coated by a layer of gold (Ag@Au) have received much attentionbecause of their potential application as ultra sensitive probes for the detection of biologicallyimportant molecules such as DNA, proteins, amino acids and many others. However, the abilityto control the size, shape, and monodispersity of the Ag@Au structure has met with limitedsuccess. In our own research we have addressed this challenge by creating an aqueous wetchemical synthesis technique towards size and shape controllable Ag@Au nanoparticles. Thesematerials are highly interesting because of the tunable silver core size, and the tunable gold shellthickness, opening many avenues to the modification of the particle properties in terms of biomolecularsensing. The resulting nanoparticle probes were functionalized with twocomplementary stranded DNA oligonucleotides. When combined, the complementary strandshybridized, causing the Ag@Au nanoparticles to assemble into large nano-structures. Thepresence of the oligonucleotide was confirmed through a series of techniques including UV-Visand Raman spectroscopy, as well as TEM, XPS, DLS, and many others. The results reflect therole that the nanoparticle physical properties play in the detection of the bio-molecules, as wellas elucidate the characteristics of the bio-molecule/nanoparticle interaction. |
| Rights: | Copyright (C) 2010 Materials Research Society. It is posted here by permission of the Materials Research Society. Derrick Mott, Nguyen T. B. Thuy, Yoshiya Aoki, and Shinya Maenosono, Materials Research Society Symposium Proceedings, 1272, 2010, PP06-12. http://www.mrs.org/ |
| URI: | http://hdl.handle.net/10119/9556 |
| Material Type: | publisher |
| Appears in Collections: | c11-1. 会議発表論文 (Conference Papers)
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