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http://hdl.handle.net/10119/9863
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| Title: | Demonstration of Three-Dimensional DNA Trapping Using Electric Force and Hydrodrag Force |
| Authors: | Ukita, Yoshiaki
Mouez, Lassoued
Tomizawa, Yuichi
Takamura, Yuzuru |
| Keywords: | DNA trapping
three-dimensional microfluidics
microfluidics
solid-phase extraction |
| Issue Date: | 2011-06-20 |
| Publisher: | The Japan Society of Applied Physics |
| Magazine name: | Japanese Journal of Applied Physics |
| Volume: | 50 |
| Number: | 6 |
| Start page: | 06GL13-1 |
| End page: | 06GL13-5 |
| DOI: | 10.1143/JJAP.50.06GL13 |
| Abstract: | This paper describes the first demonstration of DNA trapping in a stacked three-dimensional (3D) microchannel. To carry out the 3D trapping of DNA by using electric force and hydrodrag force, a 3D microchip with a stacked structure is fabricated by the conventional rapid prototyping process and SU-8 peel-off process. Experimental results show that DNA trapping is observed on the application of electric potential with continuous pumping of DNA, but it is not observed in the absence of an electric potential. Further, the results suggest that the trapping throughput of DNA clearly depends on the capillary diameter but not on the flow rate. Thus, we conclude that, for a constant trapping area, reduction in the size of capillary structures with a high density results in an increase in the efficiency of DNA trapping. |
| Rights: | This is the author's version of the work. It is posted here by permission of The Japan Society of Applied Physics. Copyright (C) 2011 The Japan Society of Applied Physics. Yoshiaki Ukita, Lassoued Mouez, Yuichi Tomizawa, and Yuzuru Takamura, Japanese Journal of Applied Physics, 50(6), 2011, 06GL13-1-06GL13-5. http://jjap.jsap.jp/link?JJAP/50/06GL13/ |
| URI: | http://hdl.handle.net/10119/9863 |
| Material Type: | author |
| Appears in Collections: | c10-1. 雑誌掲載論文 (Journal Articles)
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| 16450-1.pdf | | 852Kb | Adobe PDF | View/Open |
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