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Please use this identifier to cite or link to this item: https://hdl.handle.net/10119/8407

Title: Rewriting game theory applied to protein signalling in MAPK cascades
Authors: Senachak, Jittisak
Vestergaard, Mun'delanji
Vestergaard, Rene
Issue Date: 2006-05-31
Publisher: 北陸先端科学技術大学院大学情報科学研究科
Magazine name: Research report (School of Information Science, Japan Advanced Institute of Science and Technology)
Volume: IS-RR-2006-007
Start page: 1
End page: 15
Abstract: We propose the recent notion of rewriting game theory as a tool for studying biochemical systems. Rewriting game theory is based on a discrete and dynamic notion of Nash-style equilibria for games without structural constraints and with arbitrary payoff values. Our aim here is to show how the formalism can be used to characterise biological information as logical properties of a purely chemical model. Specifically, we address MAPK cascades through a compendium of the involved chemical reactions, with particular focus on the known signalling pathways. We also present preliminary computerised support for our methodology.
URI: https://hdl.handle.net/10119/8407
Material Type: publisher
Appears in Collections:IS-RR-2006

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