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Research Report - School of Information Science : ISSN 0918-7553 >
IS-RR-2006 >
Please use this identifier to cite or link to this item:
https://hdl.handle.net/10119/8408
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| Title: | Rewriting game theory as a foundation for state-based models of gene regulation |
| Authors: | Chettaoui, Chafika Delaplace, Franck Lescanne, Pierre Vestergaard, Mun'delanji Vestergaard, Rene |
| Issue Date: | 2006-05-31 |
| Publisher: | 北陸先端科学技術大学院大学情報科学研究科 |
| Magazine name: | Research report (School of Information Science, Japan Advanced Institute of Science and Technology) |
| Volume: | IS-RR-2006-008 |
| Start page: | 1 |
| End page: | 13 |
| Abstract: | We present a game-theoretic foundation for gene regulatory analysis based on the recent formalism of rewriting game theory. Rewriting game theory is discrete and comes with a graph-based framework for understanding compromises and interactions between players and for computing Nash equilibria. The formalism explicitly represents the dynamics of its Nash equilibria and, therefore, is a suitable foundation for the study of steady states in discrete modelling. We apply the formalism to the discrete analysis of gene regulatory networks introduced by R. Thomas and S. Kauffman. Specifically, we show that their models are specific instances of a C/P game deduced from the K parameter. |
| URI: | https://hdl.handle.net/10119/8408 |
| Material Type: | publisher |
| Appears in Collections: | IS-RR-2006
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| IS-RR-2006-008.pdf | | 801Kb | Adobe PDF | View/Open |
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